Research Profiles: 

1. Dental materials

2. Bone restoration

3. Bone regeneration

4. Biological evaluation of dental materials

Research Expertise

Areas of Research Expertise:

1.Controllable design and key property tuning of magnetic, electrical, acoustic, optical and thermal biophysical stimuli-responsive materials

2.Modulation of immunity, microbial infection and tissue regeneration by biophysical stimuli-responsive materials 

3.Machine learning-based evaluation of the safety and therapeutic efficacy of biomaterials

Research Theme: 

Artificial Intelligence, Caries, bone defect and periodontitis management

Academic Publications

1.Yunyang Bai^#，Xiaona Zheng^#，Xianwei Zhong^#，Qun Cui^#，Shuan Zhang，Xiufang Wen，Boon chin Heng，Shan He，Yang Shen，Jinxin Zhang，Yan Wei，Xuliang Deng*，Xuehui Zhang*. Manipulation of Heterogeneous Surface Electric Potential Promotes Osteogenesis by Strengthening RGD Peptide Binding and Cellular Mechanosensing. Advanced materials, 2023，35(24), e2209769. (Q1)

2.Jia Song^#, Yanhui Lu^#, Ting Pan^#, Jianfeng Wang^#, Ziqi Liu^#, Lei Xu, Siqi Zhang, Yiping Li, Yunyang Bai, Boon Chin Heng, Xiaona Zheng, Haoyan Wu, Xiaoyu Han, Yusi Guo, Qun Cui, Xuliang Deng, Xuehui Zhang*. Manipulation of surface electrical charge on nanocomposite membranes confers wide spectrum bactericidal effects and promotes tissue regeneration, Advanced Functional Materials, 2024. (Q1)

3.Wenwen Liu^#, Han Zhao^#, Chenguang Zhang^#, Shiqi Xu, Fengyi Zhang, Ling Wei, Fangyu Zhu, Ying Chen, Yumin Chen, Ying Huang, Mingming Xu, Ying He, Boon Chin Heng, Jinxing Zhang, Yang Shen, Xuehui Zhang*, Houbing Huang*, Lili Chen*, Xuliang Deng*. In situ activation of flexible magnetoelectric membrane enhances bone defect repair. Nature Communications, 2023, 14, 4091. (Q1)

4.Yingying Zhou^#, Xianfeng Ping^#, Yusi Guo, Heng^#，Boonchin, Yijun Wang, Yanze Meng, Shengjie Jiang, Yan Wei, Binbin Lai*, Xuehui Zhang*, Xuliang Deng*. (2023). Assessing Biomaterial-induced Stem Cell Lineage Fate by Machine Learning-based Artificial Intelligence. Advanced Materials, e2210637. Advance online publication. (Q1)

5.Yang Wang^#, Shuhao Wang, YanzeMeng, Zhen Liu, Dijie Li, Yunyang Bai, Guoliang Yuan, Yaojin Wang*, Xuehui Zhang*, Xiaoguang Li, Xuliang Deng*. Pyro-catalysis for tooth whitening via oral temperature fluctuation. Nature Communications, 2022, 13:4419. (Q1)

6.Jia Song^#, Wei Zhao^#, Xin Zhang, Wenyu Tian, Xuyang Zhao, Liang Ma, Yongtong Cao , Yuxin Yin*, Xuehui Zhang*, Xuliang Deng*,  Dan Lu*. Mutant RIG-I enhances cancer-related inflammation through activation of circRIG-I signaling.Nature Communications. 2022;13(1):7096. (Q1)

7.Xiaochan Li^#, Boon Chin Heng^#, Yunyang Bai, Qianqian Wang, Min Gao, Ying He, Xinwen Zhang*, Xuliang Deng*, Xuehui Zhang*. Electrical charge on ferroelectric nanocomposite membranes enhances SHED neural differentiation. Bioactive Materials, 2022;20:81-92. (Q1) 

8.Jia Song ^#, Yuning Zhang^#,Yunyang Bai Y, Xiaowen Sun,Yanhui Lu, Yusi Guo, Ying He, Min Gao, Xiaopei Chi, Boon Chin Heng, Xin Zhang, Wenjing Li, Mingming Xu, Yan Wei, Fuping You, Xuehui Zhang*,Dan Lu*, Xuliang Deng*. The Deubiquitinase OTUD1 Suppresses Secretory Neutrophil Polarization And Ameliorates Immunopathology of Periodontitis. Advanced Science. 2023;10(30). e230320. (Q1)

9.Xiaohan Dai^#, Boon Chin Heng^#, Yunyang Bai, Fuping You, Xiaowen Sun, Yiping Li, Zhangui Tang, Mingming Xu*, Xuehui Zhang*, Xuliang Deng*. Restoration of Electrical Microenvironment Enhances Bone Regeneration under Diabetic Conditions by Modulating Macrophage Polarization. Bioactive Materials. 6 (2021) 2029-2038. (Q1)

10.Lei Wang, Xuehui Zhang*, Kun Yang, Yu Vincent Fu, Tianshun Xu, Shengliang Li, Dawei Zhang, Lu-Ning Wang,* Chun-Sing Lee*. A Novel Double-Crosslinking-Double-Network Design for Injectable Hydrogels with Enhanced Tissue Adhesion and Antibacterial Capability for Wound Treatment. Advanced Functional Materials. 2019, 30(1):1904156 (Q1)

Honours and Awards

1.2023 - The top prize of the "National Disruptive Technology Innovation Competition", Ministry of Science and Technology of the People's Republic of China

2.2022 - The Chinese Stomatological Association Technology Award (First prize), The Chinese Stomatological Association (PRC)

3.2022 - The Science and Technology Improvement Award of the Scientific Research Outstanding Achievement Award in Higher Institutions (First prize), Ministry of Education of the People's Republic of China

4.2021 - NSFC Outstanding Young Scholars Program, The National Natural Science Foundation of China 2020 - The Chinese Association for Biomaterials (CAB) Trainee Award, The World Chinese Biomaterials Association (PRC)

5.2016 - The Young Elite Scientist Sponsorship Program, CAST (PRC)