Investigators

Research Profiles: 

dental pulp regeneration, bone regeneration, dental trauma, developmental abnormalities of tooth

Research Expertise

Area of Research Expertise:

The main research program focuses on the biological characteristics of dental stem cells and stem cell-based pulp and bone regeneration. In addition, some research works have been conducted on the etiology of developmental abnormalities of tooth, such as Amelogenesis Imperfecta. Also some clinical studies focus on the treatment and prognosis of traumatic dental injuries. 

Research Theme: 

  To develop materials for preserving inflamed pulp tissue

To develop scaffold for pulp and bone regeneration

To find out new candidate genes for hereditary dental anormalies

Academic Publications

1.Linxue Zhang, Zhuo Wan, Zuoying Yuan, Jun Yang, Yunfan Zhang, Qing Cai*, Jianyong Huang*, Yuming Zhao*. Construction of multifunctional cell aggregates in angiogenesis and osteogenesis through incorporating hVE-cad-Fc-modified PLGA/b-TCP microparticles for enhancing bone regeneration. J Mater Chem B. 2022 May 4;10(17):3344-3356

2.Yike Gao, Zuoying Yuan, Xiaojing Yuan, Zhuo Wan, Yingjie Yu, Qi Zhan, Yuming Zhao*, Jianmin Han, Jianyong Huang, Chunyang Xiong*, Qing Cai*. Bioinspired porous microspheres for sustained hypoxic exosomes release and vascularized bone regeneration. Bioact Mater. 2022 Aug; 14: 377–388

3.Xiaojing Yuan, Zuoying Yuan, Yuanyuan Wang, Zhuo Wan, Xiaotong Wang, Shi Yu, Jianmin Han, Jianyong Huang, Chunyang Xiong*, Lihong Ge*, Qing Cai, Yuming Zhao*. Vascularized pulp regeneration via injecting simvastatin functionalized GelMA cryogel microspheres loaded with stem cells from human exfoliated deciduous teeth. Materials Today Bio. 13 (2022) :100209

4.Zuoying Yuan, Xiaojing Yuan, Yuming Zhao*, Qing Cai, Yue Wang, Ruochen Luo, Shi Yu, Yuanyuan Wang , Jianmin Han, Lihong Ge*, Jianyong Huang, Chunyang Xiong*. Injectable GelMA Cryogel Microspheres for Modularized Cell Delivery and Potential Vascularized Bone Regeneration. Small. 2021 Mar;17(11):e2006596.  doi: 10.1002/smll.202006596. Epub 2021 Feb 23.

5.Wenjuan Yan, Fenghe Yang, Zhongning Liu, Quan Wen, Yike Gao, Xufeng Niu*, Yuming Zhao*. Anti-Inflammatory and Mineralization Effects of an ASP/PLGA-ASP/ACP/PLLA-PLGA Composite Membrane as a Dental Pulp Capping Agent. J Funct Biomater. 2022 Jul 29;13(3):106. doi: 10.3390/jfb13030106.

Honours and Awards

2011, Beijing Science and Technology Award (Third Prize) awarded by the People’s Government of Beijing Municipality

2019, Chinese Medical Science and Technology Award (Third Prize) awarded by Chinese Medical Association