Investigators

Research Profiles:

1. Mechanisms and clinical practice of oral appliances for adults with sleep disordered breathing

2. Orthodontic treatment and growth regulation for pediatric SDB

3. Phenotypes as well as morphologic and microbial mechanisms of OSA

4. Oral therapy and etiologic exploration of Catathrenia

5. Splint therapy for sleep bruxism

6. Artificial Intelligence-based Morphological Classification and Virtual Generation

Academic Publications

1. Magnetic Resonance Imaging of the Upper Airway in Obstructive Sleep Apnea before and after Oral Appliance Therapy. The Chinese Journal of Dental Research,1999.

2.Effect of Titrated Mandibular Advancement and Jaw Opening on the Upper Airway in Awake Non-Apnea Individuals: A Magnetic Resonance Imaging and Cephalometric Study. Am J Orthod Dentofacial Orthop, 2004.

3. An Adjustable Appliance in Treatment of Obstructive Sleep Apnea-Hypopnea Syndrome. The Chinese Journal of Dental Research, 2005.

4. A case-control study of craniofacial features of children with obstructed sleep apnea. Sleep Breathing, 2012.

5. Long-term therapeutic efficacy of oral appliances in treatment of obstructive sleep apnea-hypopnea syndrome. Angle Orthodontist,.

6.MRI of the upper airway in non-snoring males. A comparative study in children and adults. Somnologie, 2013.

7. A prospective CBCT study of upper airway changes after rapid maxillary expansion.  International Journal of Pediatric Otorhinolaryngology, 2013.

8. Anatomical characteristics of catathrenia (nocturnal groaning) in upper airway and orofacial structures. Sleep Breath. 2015.

9. Upper Airway Changes after Orthodontic Extraction Treatment in Adults: a Preliminary Study using Cone Beam Computed Tomography. PLoS One. 2015.

10. Three-dimensional evaluation of the upper airway in children of skeletal class III. Journal of Cranio facial Surgery. 2017.

11. Effects of craniofacial morphology on nasal respiratory function and upper airway morphology.  J Craniofac Surg 2018.

12. Tongue pressure distribution of individual normal occlusions and exploration of related factors. J Oral Rehabil. 2019.

13. Mandibular advancement appliances for the treatment of obstructive sleep apnea in children: a systematic review and meta-analysis. Sleep Medicine. 2019.

14. The effect of gradually increased mandibular advancement on the efficacy of oral appliance in the treatment of obstructive sleep apnea. Journal of clinical sleep medicine. 2020.

15. Differences of Craniofacial Characteristics in Oral Breathing and Pediatric OSA. J Craniofac Surg 2021.

16. Polysomnographic characteristics and acoustic analysis of catathrenia (nocturnal groaning). Physiol Meas. 2020.

17. Mandibular advancement device as treatment trial for catathrenia (nocturnal groaning). Journal of clinical sleep medicine 2021.

18. The interaction of obesity and craniofacial deformity in Obstructive Sleep Apnea. Dentomaxillofacial Radiology. 2021.

19. Analysis of Salivary Microbiome and Its Association With Periodontitis in Patients With Obstructive Sleep Apnea. Front Cell Infect Microbiol. 2021.

20. A cone beam CT study of upper airway morphology in perimenopausal and postmenopausal women. Int J Womens Health . 2021.

21. Association between obstructive sleep apnea and periodontitis in Chinese male adults: A cross-sectional study. The Journal of Prosthetic Dentistry 2021.

22. Altered Salivary Microbiota in Patients with Obstructive Sleep Apnea Comorbid Hypertension. Nat Sci Sleep. 2022.

23. Characteristics of salivary microbiota in children with obstructive sleep apnea: A prospective study with polysomnography. Front Cell Infect Microbiol. 2022.

24. Quantitative changes of upper airway in class III patients undergoing bimaxillary surgery after one-year follow-up: a retrospective study. Head Face Med. 2022.

25. Convolutional neural network-based automatic cervical vertebral maturation classification method. Dentomaxillofac Radiol. 2022.

26. Automatic Classification for Sagittal Craniofacial Patterns Based on Different Convolutional Neural Networks. Diagnostics (Basel). 2022.

27. . Study of facial generation methods after orthodontic treatment. 2022 IEEE 46th Annual Computers, Software, and Applications Conference (COMPSAC).

28. Role of craniofacial phenotypes in the response to oral appliance therapy for obstructive sleep apnea. J Oral Rehabil. 2023.

29. Anatomical phenotype of obstructive sleep apnea patients based on cluster analysis. Orthod Craniofac Res. 2023.

30. Age-related hypertrophy of adenoid and tonsil with its relationship with craniofacial morphology. BMC Pediatr. 2023.

31. Orthodontic appliances for the treatment of pediatric obstructive sleep apnea: A systematic review and network meta-analysis. Sleep Med Rev. 2023.

32. Long-term efficacy of mandibular advancement devices in the treatment of adult obstructive sleep apnea: A systematic review and meta-analysis. PLoS One. 2023.

33. Self-reported sleep status and influencing factors: a web-based national cross-sectional survey in China. Ann Med. 2023.

34. Relationship Between Sleep Duration and Cognitive Function in Older Adults: Analysis of NHANES and UK Biobank GWAS Data. Biol Res Nurs. 2024.

35. Dental and Skeletal Changes of Long-term Use of Mandibular Advancement Devices for the Treatment of Adult Obstructive Sleep Apnea: a Systematic Review and Meta-analysis. Journal of Evidence-Based Dental Practice 2024.

36. Clinical features of non-syndromic late developing supernumerary teeth: a sign of the third dentition  BMC Oral Health. 2024.

37. Assessing the causal association between sleep apnea and the human gut microbiome composition: A two-sample Mendelian randomization study. SAGE Open Med. 2024 

38. Association of night-time sleep and daytime napping with painful temporomandibular disorder. J Oral Rehabil. 2024.

39. Differences in Polysomnographic and Craniofacial Characteristics of Catathrenia Phenotypes: A Cluster Analysis. Nat Sci Sleep. 2024.

40. Relationships between orofacial pain and sleep: Analysis of UK biobank and genomewide association studies data. Journal of dental sciences.2024.

41. Differences in salivary microbiome among children with tonsillar hypertrophy and/or adenoid hypertrophy. mSystems. 2024 .

Honours and Awards

1. Third Prize, Ministry of Education Prize for Progress in Science and Technology, 1999

2. Second Prize, Nominated by the Ministry of Education Prize for Progress in Science and Technology, 2003

3. Second Prize, Chinese Medical Science and Technology Prize, 2004

4. Best Paper Award, the 4th annual Academic meeting of CSRS, 2006

5. Leading 5000 Academic Papers of Chinese top science and technology journals, 2013

6. Third Prize，4th Industry and Research Cooperation Award of Peking University, 2019