Investigators

Research Profiles: 

Orthodontic treatment; Orthodontic appliances; Craniofacial growth and development; Digital diagnosis and treatment; Tissue engineering and biomaterials; Functional biomimetic ceramics; Biomechanics

Academic Publications

1.Nan Li，Hao Qin, Fei Zhu, Hao Ding, Yang Chen, Yixuan Lin, Ronghui Deng, Tianyu Ma, Yuanyuan Lv, Changhao Xiong, Rong Li, Yaohua Wei, Jian Shi, Hanqing Chen, Guangbiao Zhou,Yuliang Zhao, Bing Han*, Guangjun Nie*, Ruifang Zhao*, Harnessing the tumor-shared antigens of induced pluripotent stem cell membranes to generate potent tumor vaccines for multiple cancer prevention. Nature Biomedical Engineering，2024 

2.Tingting Yu, Rushui Bai, Zeming Wang, Yuting Qin, Jingwei Wang, Yaohua Wei, Ruifang Zhao*, Guangjun Nie*, Bing Han*. Colon-targeted Engineered Postbiotics Nanoparticles Alleviating Osteoporosis through Gut-Bone Axis.  Nature Communications,2024

3.Bo Wu, Huijing Zheng, Yan-Qi Wu, Zhicheng Huang, Hao-Cheng Thong, Hong Tao, Jian Ma, Chunlin Zhao*, Ze Xu, Yi-Xuan Liu, Zhipeng Xing, Naixin Liang, Fang-Zhou Yao*, Chao-Feng Wu, Ke Wang & Bing Han*. Origin of ultrahigh-performance barium titanate-based piezoelectrics: Stannum induced intrinsic and extrinsic contributions, Nature Communications. 2024.

4.Bo Wu, Lin Zhao, Jiaqing Feng, Yiting Zhang, Xilong Song, Jian Ma , Hong Tao, Ze Xu，Yi-Xuan Liu, Shidong Wang*, Jingtong Lu, Fangyuan Zhu , Bing Han* and Ke Wang *. Contribution of irreversible non-180o domain to performance for multiphase coexisted potassium sodium niobate ceramics. Nature Communications. 2024

5.Hao Liu, Yuning Zhang, Yunfan Zhang, Yiping Huang, Yuhui Yang, Yi Zhao, Si Chen*, Jie Deng*, Weiran Li*, Bing Han*. PDLC-apoptosis activates Lepr+ osteoprogenitors in orthodontics. Journal of Dental Research, 2024（封面论文）

6.Di Zhao, Lei Guo, Qianrui Li, Chunmei Yue, Bing Han,* Kai Liu,* and Huanrong Li*：Multi-functional Lanthanide Metallopolymer: Self-healing and Photo-stimuli-responsive Dual-emitting Luminescence for Diverse Applications， Advanced Materials. 2024

7.Yangyong Sun#, Zengzhen Chen#, Huiping Gong, Xueqiao Li, Zhenfei Gao, Shichen Xu, Xiaodong Han, Bing Han,* Xianwei Meng,* and Jin Zhang*. Continuous “Snowing” Thermotherapeutic Graphene. Advanced Materials. 2020

8.Yi-Xuan Liu, Wanbo Qu, Hao-Cheng Thong, Yang Zhang, Yunfan Zhang, Fang-Zhou Yao, Trong Nghia Nguyen, Jia-Wang Li, Mao-Hua Zhang, Jing-Feng Li*, Bing Han*, Wen Gong, Haijun Wu, Chaofeng Wu, Ben Xu, Ke Wang*. Isolated-Oxygen-Vacancy Hardening in Lead-Free Piezoelectrics. Advanced Materials. 2022

9.Qiannan Sun, Zimeng Zhuang, Rushui Bai, Jie Deng, Tianyi Xin, Yunfan Zhang, Qian Li*, Bing Han*. Lysine 68 Methylation-dependent SOX9 Stability Control Modulates Chondrogenic Differentiation in Dental Pulp Stem Cells. Advanced Science, 2023

10.Tingting Yu; Lingyun Zhang; Xueyu Dou; Rushui Bai; Hufei Wang; Jie Deng; Yunfan Zhang; Qiannan Sun; Qian Li; Xing Wang*; Bing Han* ; Mechanically Robust Hydrogels Facilitating Bone Regeneration through Epigenetic Modulation, Advanced Science, 2022

11.Yunfan Zhang, Xueyu Dou, Lingyun Zhang, Hufei Wang, Ting Zhang, Rushui Bai, Qiannan Sun, Xing Wang*, Tingting Yu*, Decheng Wu, Bing Han*, Xuliang Deng. Facile fabrication of a biocompatible composite gel with sustained release of aspirin for bone regeneration. Bioactive Materials. 2022

12.Tingting Yu, Jingwei Wang, Yusai Zhou, Chao Ma, Rushui Bai, Cancan Huang, Shidong Wang*, Kai Liu*, and Bing Han*, Engineered extracellular vesicles from mesenchymal stem cells as a therapeutic strategy for bone-related diseases. Advanced Functional Materials，2024,

13.Yi-Xuan Liu, Jinling Zhou, Yuqi Jiang, Chen-Bo-Wen Li, Chao Li, Jing-Tong Lu, Ze Xu,Fang-Zhou Yao,* Hu Nan, Dawei Wang, Liqiang Xu, Yicheng Wang, Yijia Du, Jingkai Nie,Zhixiang Zhu,* Wen Gong,* Bing Han,* and Ke Wang：Multi-Length Engineering of (K,Na)NbO3 Films for Lead-Free Piezoelectric Acoustic Sensors with High Sensitivity，Advanced Functional Materials，2023

14.Mao-Hua Zhang,，Qinghua Zhang,，Ting-Ting Yu,， Geng Li, Hao-Cheng Thong, Li-Ying Peng, Lisha Liu, Jing Ma, Yang Shen, Zhijian Shen, John Daniels, Lin Gu, Bing Han,* Long-Qing Chen, Jing-Feng Li, Fei Li,* and Ke Wang,*. Enhanced electric-field-induced strains in (K,Na)NbO3 piezoelectrics from heterogeneous structures. Materials Today， 2021

15.Yunfan Zhang，Jiale Yan，Yuning Zhang，Hao Liu，Bing Han*，Weiran Li，Age-related alveolar bone maladaptation in adult orthodontics: finding new ways out，International Journal of Oral Science，2024

16.Jie Deng; Zi-Meng Zhuang; Xiao Xu; Bing Han*; Guang-Ying Song*; Tian-Min Xu*. Mechanical Force Increases Tooth Movement and Promotes Remodeling of Alveolar Bone Defects Augmented with Bovine Bone Minera，Progress in Orthodontics. 2024

17.Huanhuan Chen, Guangying Song, *, Yi Fan, Jiuhui Jiang, Ruoping Jiang, Xiaoyun Zhang, Gui Chen, Hong Su, Tianyi Wang, Bing Han, * and Tianmin Xu. Evaluating anchorage and torque control in Class II division 1 adolescent patients among three appliances，American Journal of Orthodontics and Dentofacial Orthopedics ,2024

18.Hao Liu; Yuning Zhang; Wenhsuan Lu; Yuhui Yang; Xiaomo Liu; Si Chen; Weiran Li; Bing Han*，Lower incisor position in skeletal Class III malocclusion patients: a comparative study of orthodontic camouflage and orthognathic surgery, Angle Orthodontist，2024

19.Wenhsuan Lu#，Guangying Song# ,Qiannan Sun , Liying Peng ,Yunfan Zhang ,Bing Han*，Jiuxiang Lin. Analysis of Facial Features and Prediction of Lip Position in Skeletal Class Ⅲ Malocclusion Adult Patients Undergoing Surgical-Orthodontic Treatment. Clinical Oral Investigations. 2021

20.Qiannan Sun, Rushui Bai, Si Chen*, Zimeng Zhuang, Jie Deng, Tianyi Xin, Yunfan Zhang, Qian Li*, Bing Han*. Lysine demethylase 3A promotes chondrogenic differentiation of aged human dental pulp stem cells, Journal of Dental Sciences.2024

21.Yao Tang, Wenhsuan Lu, Weiqiang Wu, Qiannan Sun, Yunfan Zhang,Tianmin Xu, Si Chen*, Wei Liang* and Bing Han*. Alveolar bone morphology in patients with palatally-displaced maxillary lateral incisors before and after orthodontic treatment: a cone-beam computed tomography study. Orthodontics & Craniofacial Research，2024

22.Huanhuan Chen#, Guangying Song#, Weiran Li, Ruoping Jiang, Xiaoyun Zhang, Si Chen, Gui Chen, Siqi Liu, Fanfan Dai, Fei Teng, Bing Han*, Tianmin Xu*. Subjective and objective analysis of orthodontic expert consensus on the assessment of orthodontic treatment outcomes. Orthodontics & Craniofacial Research，2023

23.Zhao Li#, Hao-Cheng Thong#, Yun-Fan Zhang#, Ze Xu, Zhen Zhou, Yi-Xuan Liu, Yue-Yu-Shan Cheng, Shi-Hong Wang, Chun-Lin Zhao, Feng Chen, Ke Bi*, Bing Han* and Ke Wang*. Defect Engineering in Lead Zirconate Titanate Ferroelectric Ceramic for Enhanced Electromechanical Transducer Efficiency. Advanced Functional Materials. 2020

24.Lingyun Zhang, Yunfan Zhang, Tingting Yu, Liying Peng, Qiannan Sun, Bing Han*. Engineered fabrication of enamel-mimetic materials. Engineering. 2022

25.Tianyi Xin, Qian Li, Rushui Bai, Ting Zhang, Yanheng Zhou, Yuehua Zhang, Bing Han* and Ruili Yang*. A novel mutation of SATB2 inhibits odontogenesis of human dental pulp stem cells through Wnt/beta-catenin signaling pathway. Stem Cell Research & Therapy. 2021 

26.Jianhan Ren, Melissa Rachel Fok, Yunfan Zhang, Bing Han*, Yifan Lin*. The role of non-steroidal anti-inflammatory drugs as adjuncts to periodontal treatment and in periodontal regeneration, Journal of translational medicine，2023

27.Liying Peng, Li Chang, Mengting Si, Jiuxiang Lin, Shutao Wang, Hongliang Liu, * Bing Han *and Lei Jiang. Hydrogel-coated Dental Device with Adhesion-inhibiting and Colony-suppressing Properties. ACS Applied Materials & Interfaces. 2020

28.Fanfan Dai, Si Chen, Tingting Feng, Wenhsuan Lu, Gui Chen, Jiuhui Jiang, Ruoping Jiang, Jiuxiang Lin, Bing Han*, Tianmin Xu*. Accuracy of integration of dental cast and cephalograms compared with cone-beam computed tomography: a comparative study. Odontology, 2023

29.Yiran Jiang, Guangying Song, Xiaonan Yu, Yuanbo Dou, Qingfeng Li, Siqi Liu, Bing Han* and Tianmin Xu*. The application and accuracy of feature matching on automated cephalometric superimposition（Featured Article）. BMC Medical Imaging. 2020

30.Xi Liu, Liying Peng, Jingxin Meng*, Zhongpeng Zhu, Bing Han*. Protein-Mediated Anti-Adhesion Surface against Oral Bacteria. Nanoscale. 2018

31.Liying Peng, Li Chang, Xi Liu, Jiuxiang Lin, Hongliang Liu*, Bing Han*, Shutao Wang*. Antibacterial Property of a Polyethylene Glycol-grafted Dental Material. ACS Applied Materials & Interfaces. 2017

32.An Xing, Qiannan Sun, Yan Meng*, Yongyi Zhang, Xiaoyu Li *, Bing Han, *. A hydroxyl-containing hyperbranched polymer as a multi-purpose modifier for a dental epoxy. Reactive and Functional Polymers. 2020

33.Jiayu Pan，Tianlu Men，Xingyu Xu，Ze Xu，Qi Li，Xiang-Cheng Chu，Yang Shen*, Bing Han*，Ke Wang. Domain growth dynamics in PMN-PT ferroelectric thin films，Journal of Materials Science，2019

Honours and Awards

2021 National High-Level Talents Special Support Program (Leading Talent of Technological Innovation of Ten-Thousands Talents Program)

2020 Innovation Leadership Program in Sciences and Technologies for Young and Middle-aged Scientists, National Ministry of Science and Technology

2022 Prize for Outstanding Doctor of Peking University

2020 Second Prize of Chinese Stomatology Science and Technology Award

2019 Second Prize of Beijing Medical Science and Technology Award