Investigators

Research Profiles: 

1. The relationship between periodontitis and systemic diseases

2. Mitochondrial DNA and susceptibility of aggressive periodontitis

3. iPSCs and periodontal tissue regeneration

4. The role of EGCG in treatment of periodontitis

Academic Publications

1. MFN2 silencing promotes neural differentiation of embryonic stem cells via the Akt signaling pathway.Yi S, Cui C, Huang X, Yin X, Li Y, Wen J, Luan Q.J Cell Physiol. 2019 Jul 5. doi: 10.1002/jcp.29020.

2. The Effect of Ultrasound, Oxygen and Sunlight on the Stability of (-)-Epigallocatechin Gallate.Zeng J, Xu H, Cai Y, Xuan Y, Liu J, Gao Y, Luan Q.Molecules. 2018 Sep 18;23(9). pii: E2394. doi: 10.3390/molecules23092394.

3. P53 mediates lipopolysaccharide-induced inflammation in human gingival fibroblasts.Liu J, Zeng J, Wang X, Zheng M, Luan Q.J Periodontol. 2018 Sep;89(9):1142-1151.

4. Lipopolysaccharide from Porphyromonas gingivalis promotes autophagy of human gingival fibroblasts through the PI3K/Akt/mTOR signaling pathway.Liu J, Wang X, Zheng M, Luan Q.Life Sci. 2018 Oct 15;211:133-139.

5. Comparative study of periodontal differentiation propensity of induced pluripotent stem cells from different tissue origins.Li J, Yin X, Luan Q.J Periodontol. 2018 Oct;89(10):1230-1240.

6. Tanshinone IIA Attenuates Atherosclerosis in Apolipoprotein E Knockout Mice Infected with Porphyromonas gingivalis.Xuan Y, Gao Y, Huang H, Wang X, Cai Y, Luan QX.Inflammation. 2017 Oct;40(5):1631-1642.

7. Porphyromonas gingivalis Infection Accelerates Atherosclerosis Mediated by Oxidative Stress and Inflammatory Responses in ApoE-/- Mice.Xuan Y, Shi Q, Liu GJ, Luan QX, Cai Y.Clin Lab. 2017 Oct 1;63(10):1627-1637.

8. Growth/differentiation factor-5 promotes in vitro/vivo periodontal specific differentiation of induced pluripotent stem cell-derived mesenchymal stem cells.Yin X, Li P, Li Y, Cai Y, Wen J, Luan Q.Exp Ther Med. 2017 Nov;14(5):4111-4117.

9. Generation and periodontal differentiation of human gingival fibroblasts-derived integration-free induced pluripotent stem cells.Yin X, Li Y, Li J, Li P, Liu Y, Wen J, Luan Q.Biochem Biophys Res Commun. 2016 May 6;473(3):726-32.

10. Mitochondrial reactive oxygen species mediate the lipopolysaccharide-induced pro-inflammatory response in human gingival fibroblasts.Li X, Wang X, Zheng M, Luan QX.Exp Cell Res. 2016 Sep 10;347(1):212-21.

11. Association of cognitive function with tooth loss and mitochondrial variation in adult subjects: a community-based study in Beijing, China.Gao W, Wang X, Wang X, Cai Y, Luan Q.Oral Dis. 2016 Oct;22(7):697-702.

12. Green tea epigallocatechin-3-gallate alleviates Porphyromonas gingivalis-induced periodontitis in mice.Cai Y, Chen Z, Liu H, Xuan Y, Wang X, Luan Q.Int Immunopharmacol. 2015 Dec;29(2):839-845.

13. Association of mitochondrial DNA displacement loop polymorphisms and aggressive periodontitis in a Chinese population: a pilot study.Wang X, Guo Y, Luan Q.Mitochondrial DNA. 2015 Jun;26(3):389-95.

14. Association of Carotid Intima-media Thickness and Atherosclerotic Plaque with Periodontal Status.Yu H, Qi LT, Liu LS, Wang XY, Zhang Y, Huo Y, Luan QX.J Dent Res. 2014 Aug;93(8):744-51.

15. Mitochondrial polymorphisms and dysfunction related to aggressive periodontitis: a pilot study.Wang X, Luan Q, Chen Q, Zhao L, Guo Y.Oral Dis. 2014 Jul;20(5):490-8.